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Dr. Greg Dussor’s research focus is on uncovering pathological mechanisms and therapeutic targets for migraine headache. Since the most likely mechanism contributing to migraine pain is activation of peripheral nociceptive signaling from the meninges, experiments in the Dussor laboratory have focused on identifying cellular mechanisms of dural afferent activation/sensitization as well as understanding plasticity at the central terminals of these neurons. The laboratory has identified targets within the meningeal nociceptive system including acid-sensing ion channels (ASICs), several TRP channels, and IL-6 signaling mechanisms. His team has also developed and optimized several preclinical behavioral models for studying migraine. More recently, they have begun to investigate mechanisms that may contribute to the higher prevalence of migraine in women. These studies include a...

K.C. Brennan, MD, is a clinician scientist who specializes in the treatment of headache. disorders. His lab studies the basic mechanisms of migraine and post-traumatic headache. Dr. Brennan's laboratory studies derangements of brain excitability. A particular interest is cortical spreading depression (CSD), a wave of runaway excitation that is thought to be the basis of the migraine aura. CSD is also involved in traumatic brain injury, stroke, and epilepsy. The lab uses a combination of techniques including optical intrinsic signal imaging and spectroscopy, voltage sensitive dye imaging, two-photon microscopy, and electrophysiology to study CSD and the disorders it affects....

Gisela Terwindt received her MSc in Biology and MD in Medicine at the University of Leiden, the Netherlands. Her PhD encompassed epidemiology and genetics of migraine, with the discovery of the first migraine gene. She is associate professor of Neurology, and Consultant Neurologist, at the Department of Neurology, Leiden University Medical Center (LUMC), Netherlands, where she also runs the Headache Clinic. Gisela Terwindt is chair of the scientific committee of the Dutch Headache Society. She is member of the International Headache Classification Committee, the IHS Ethics Committee, and chair of the IHS Women’s Leadership Forum. She has published >150 scientific papers and several book chapters on headache and migraine.  She received a prestigious personal grant from the Dutch Organisation of Scientific Research...

Faisal Mohammad Amin, MD, PhD, is an Associate Professor of Neurology at the University of Copenhagen, Denmark, and the current President of the Danish Headache Society. He is also a Senior Consultant in Neurology at the Danish Headache Center, Rigshospitalet, Denmark. Dr. Amin has authored more than 80 peer-reviewed publications and his academic works focus on the use of advanced magnetic resonance imaging to investigate structural and functional cerebral biomarkers of migraine. He is considered among the leading experts on migraine and post-traumatic headache worldwide. Dr. Amin is on the editorial board of Cephalalgia and The Journal of Headache and Pain. He is also on the Board of Directors of the European Headache Federation and has previously been a Board Member of...